Cationic Liposomes Carrying HPV16 E6-siRNA Inhibit the Proliferation, Migration, and Invasion of Cervical Cancer Cells

The E6 and E7 oncoproteins of high-risk types of human papillomavirus (HR-HPV) are crucial for the development of cervical cancer (CC). Small interfering RNAs (siRNAs) are explored as novel therapies that silence these oncogenes, but their clinical use is hampered by inefficient delivery systems. Mo...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Luz Victoria Sánchez-Meza, Ciresthel Bello-Rios, Josimar O. Eloy, Yazmín Gómez-Gómez, Marco Antonio Leyva-Vázquez, Raquel Petrilli, María Josefa Bernad-Bernad, Alfredo Lagunas-Martínez, Luis Alberto Medina, Janeth Serrano-Bello, Jorge Organista-Nava, Berenice Illades-Aguiar
Format:	Article
Language:	English
Published:	MDPI AG 2024-06-01
Subjects:	cervical cancer E6 oncoprotein HPV16 E6 siRNAs lipoplexes liposomes
Online Access:	https://www.mdpi.com/1999-4923/16/7/880