Boosting with Multiple Doses of mRNA Vaccine after Priming with Two Doses of Protein Subunit Vaccine MVC-COV1901 Elicited Robust Humoral and Cellular Immune Responses against Emerging SARS-CoV-2 Variants

ABSTRACT Confronted with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, such as Delta and Omicron, with high infectivity and immune evasion capacity, vaccination remains the most effective tool to prevent infection and severe illness. However, heterologous vaccination of mRNA...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Chun-Hsiang Chiu, Yu-Hsiu Chang, Chi-Wei Tao, Feng-Yee Chang, Kuo-Chou Chiu, Tien-Wei Chang, Li-Chen Yen
Format:	Article
Language:	English
Published:	American Society for Microbiology 2022-10-01
Subjects:	SARS-CoV-2 viral variants heterologous vaccination protein subunit vaccine neutralizing antibody cellular immune response
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00609-22