XIST Loss Induces Variable Transcriptional Responses Dependent on Cell States

<b>Background/Objectives</b>: The X-inactivation specific transcript (XIST) is a long noncoding RNA playing a crucial regulatory role in X chromosome inactivation (XCI)—a transcriptional regulatory process that silences one of the two X chromosomes in females to ensure proper dosage comp...

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Bibliographic Details
Published in:Non-Coding RNA
Main Authors: Dongning Chen, Ikrame Naciri, Jie Wu, Sha Sun
Format: Article
Language:English
Published: MDPI AG 2025-09-01
Subjects:
Online Access:https://www.mdpi.com/2311-553X/11/5/67