FGFR2 expression relates to subtype-specific tumour microenvironment (TIME) during luminal breast cancer evolution

BackgroundFibroblast growth factor receptor 2 (FGFR2) is an oncogenic driver in luminal breast cancer (BCa), with emerging evidence linking it to tumour immune microenvironment (TIME) modulation. While FGFR2’s role in endocrine resistance is established, its potential involvement in shaping immune i...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Julia Sołek, Aleksandra Zielińska, Radzisław Kordek, Hanna Romańska, Marcin Braun
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	breast cancer ductal carcinoma in situ invasive breast cancer tumour immunemicroenvironment tumour-infiltrating lymphocytes tumour-associated macrophages
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1655438/full