A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence

Bacteriophage repressor proteins downregulate viral lytic gene expression. Herein, the authors present the X-ray crystal structure of a monomeric repressor that binds an asymmetric DNA sequence using two independent domains.

Bibliographic Details
Published in:Nature Communications
Main Authors: Reliza J. McGinnis, Chad A. Brambley, Brandon Stamey, William C. Green, Kimberly N. Gragg, Erin R. Cafferty, Thomas C. Terwilliger, Michal Hammel, Thomas J. Hollis, Justin M. Miller, Maria D. Gainey, Jamie R. Wallen
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Online Access:https://doi.org/10.1038/s41467-022-31678-6

Internet

https://doi.org/10.1038/s41467-022-31678-6

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