Rational Design of and Mechanism Insight into an Efficient Antifreeze Peptide for Cryopreservation

The development of effective antifreeze peptides to control ice growth has attracted a significant amount of attention yet still remains a great challenge. Here, we propose a novel design method based on in-depth investigation of repetitive motifs in various ice-binding proteins (IBPs) with evolutio...

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Bibliographic Details

Published in:	Engineering
Main Authors:	Haishan Qi, Yihang Gao, Lin Zhang, Zhongxin Cui, Xiaojie Sui, Jianfan Ma, Jing Yang, Zhiquan Shu, Lei Zhang
Format:	Article
Language:	English
Published:	Elsevier 2024-03-01
Subjects:	Antifreeze peptides Evolution analysis Ice recrystallization inhibition Molecular dynamics simulation Cryopreservation Synthetic biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2095809923002114