Isolation and purification of DNA double-strand break repair intermediates for understanding complex molecular mechanisms.

Branched DNA molecules are key intermediates in the molecular pathways of DNA replication, repair and recombination. Understanding their structural details, therefore, helps to envisage the mechanisms underlying these processes. While the configurations of DNA molecules can be effectively analysed i...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Tahirah Yasmin, Benura Azeroglu, Fares Osam Yanez-Cuna, Sally Jones, Patrick Yizhi Cai, David R F Leach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Online Access:https://doi.org/10.1371/journal.pone.0308786