Loss of transcriptional heterogeneity in aged human muscle stem cells.

Age-related loss of muscle mass and function negatively impacts healthspan and lifespan. Satellite cells function as muscle stem cells in muscle maintenance and regeneration by self-renewal, activation, proliferation and differentiation. These processes are perturbed in aging at the stem cell popula...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Emilie Barruet, Katharine Striedinger, Pauline Marangoni, Jason H Pomerantz
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0285018