A Simple and Sensitive LC-MS/MS for Quantitation of ICG in Rat Plasma: Application to a Pre-Clinical Pharmacokinetic Study

A selective, sensitive, and rapid liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantitation of ICG in rat plasma. The chromatographic separation was achieved using an ACE excel C18 (3 µm, 50 × 3.0 mm) column, with a mobile phase co...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Separations
المؤلفون الرئيسيون:	Yashpal S. Chhonker, Nicholas E. Wojtynek, Prachi Agrawal, Aaron M. Mohs, Daryl J. Murry
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2023-01-01
الموضوعات:	ICG LC-MS/MS rat plasma validation pharmacokinetics intravenous
الوصول للمادة أونلاين:	https://www.mdpi.com/2297-8739/10/2/66