A backbone-based flow cytometry approach to decipher regulatory T cell trajectories in the human thymus

Thymus-committed regulatory T cells (Tregs) are essential for immune homeostasis. Recent findings stress their heterogeneity, suggesting possible alternate routes for thymic Treg development with unique features in humans, namely the clear evidence of Treg commitment at the double-positive (DP) stag...

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發表在:	Frontiers in Immunology
Main Authors:	Beatriz Moleirinho, Margarida Paulo-Pedro, Nicole C. Martins, Emily Jelagat, Eller Conti, Tiago R. Velho, Miguel Abecasis, Rui Anjos, Afonso R. M. Almeida, Ana E. Sousa
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2025-03-01
主題:	thymus human immunology regulatory T cells T cell development spectral flow cytometry
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1553535/full