SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients

Summary: Patients with COVID-19 may develop abnormal inflammatory response, followed in some cases by severe disease and long-lasting syndromes. We show here that in vitro exposure to SARS-CoV-2 activates the expression of the human endogenous retrovirus (HERV) HERV-W proinflammatory envelope protei...

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發表在:	iScience
Main Authors:	Benjamin Charvet, Joanna Brunel, Justine Pierquin, Mathieu Iampietro, Didier Decimo, Nelly Queruel, Alexandre Lucas, María del Mar Encabo-Berzosa, Izaskun Arenaz, Tania Perez Marmolejo, Arturo Ivan Gonzalez, Armando Castorena Maldonado, Cyrille Mathieu, Patrick Küry, Jose Flores-Rivera, Fernanda Torres-Ruiz, Santiago Avila-Rios, Gonzalo Salgado Montes de Oca, Jon Schoorlemmer, Hervé Perron, Branka Horvat
格式:	Article
語言:	英语
出版:	Elsevier 2023-05-01
主題:	Health sciences Virology Molecular Genetics
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2589004223006818