NF-κB activation impedes the transdifferentiation of hypertrophic chondrocytes at the growth plate of mouse embryos in diabetic pregnancy

Background: Diabetes mellitus could cause numerous complications and health problems including abnormality of endochondral bone formation during embryogenesis. However, the underlying mechanisms still remain obscure. Methods: Streptozotoci (STZ) was injected to induce pregestational diabetes mellitu...

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書誌詳細

出版年:	Journal of Orthopaedic Translation
主要な著者:	Xi Liu, Fan Qian, Qiwei Fan, Li Lin, Meiyao He, Peizhi Li, Hongmei Cai, Lisha Ma, Xin Cheng, Xuesong Yang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2021-11-01
主題:	Diabetes mellitus Endochondral bone formation Growth plate Hypertrophic zone NF-ĸB signaling bone morphogenetic protein 2, Bmp2
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2214031X21000929