Immune escape of Staphylococcus aureus mediated by osteocyte lacuna-canalicular network leads to persistent and uncured bone infection

Bone infections, specifically chronic osteomyelitis, are characterized by recurrent episodes. They are considered intractable clinical diseases as they require protracted and difficult-to-cure courses. Staphylococcus aureus (S. aureus) is the most common pathogen responsible for bone infections and...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Zhigang Rong, Xiaozhen Chen, Leilei Qin, Xiaohua Wang, Fei Luo, Quanming Zou, Hao Zeng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	Staphylococcus aureus osteocyte lacuno-canalicular network immune escape bone infection chronic osteomyelitis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1592086/full