Role of aquaporin-4 polarization in extracellular solute clearance

Abstract Waste from the brain has been shown to be cleared via the perivascular spaces through the so-called glymphatic system. According to this model the cerebrospinal fluid (CSF) enters the brain in perivascular spaces of arteries, crosses the astrocyte endfoot layer, flows through the parenchyma...

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Bibliographic Details

Published in:	Fluids and Barriers of the CNS
Main Authors:	Laura Bojarskaite, Sahar Nafari, Anne Katrine Ravnanger, Mina Martine Frey, Nadia Skauli, Knut Sindre Åbjørsbråten, Lena Catherine Roth, Mahmood Amiry-Moghaddam, Erlend A. Nagelhus, Ole Petter Ottersen, Inger Lise Bogen, Anna E. Thoren, Rune Enger
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Subjects:	AQP4 Glymphatic Waste clearance Astrocyte Glia Syntrophin
Online Access:	https://doi.org/10.1186/s12987-024-00527-7