TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils

[INLINE:1] Microglia-mediated neuroinflammation is considered a pathological feature of Parkinson’s disease. Triggering receptor expressed on myeloid cell-1 (TREM-1) can amplify the inherent immune response, and crucially, regulate inflammation. In this study, we found marked elevation of serum solu...

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Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Tong Shen, Guiyun Cui, Hao Chen, Long Huang, Wei Song, Jie Zu, Wei Zhang, Chuanying Xu, Liguo Dong, Yongmei Zhang
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2024-01-01
Subjects:	1-methyl-4-phenylpyridiniumion; dopaminergic neurons; infiltration; 1-methyl-4-phenyl-1 2 3 6-tetrahydropyridine; microglia; neutrophils; neuroinflammation; parkinson’s disease; syk; trem-1
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=6;spage=1375;epage=1384;aulast=Shen