Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor Etv2.

Etsrp/Etv2 (Etv2) is an evolutionarily conserved master regulator of vascular development in vertebrates. Etv2 deficiency prevents the proper specification of the endothelial cell lineage, while its overexpression causes expansion of the endothelial cell lineage in the early embryo or in embryonic s...

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Bibliographic Details
Published in:PLoS Biology
Main Authors: Matthew B Veldman, Chengjian Zhao, Gustavo A Gomez, Anne G Lindgren, Haigen Huang, Hanshuo Yang, Shaohua Yao, Benjamin L Martin, David Kimelman, Shuo Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Online Access:http://europepmc.org/articles/PMC3708712?pdf=render