Porphyromonas gingivalis and Its Outer Membrane Vesicles Induce Neuroinflammation in Mice Through Distinct Mechanisms

ABSTRACT Background Alzheimer's disease (AD) is the most common chronic neurodegenerative disorder, with neuroinflammation playing an important role in its progression to become a major research focus. The role of Porphyromonas gingivalis (Pg) and its outer membrane vesicles (Pg OMVs) in AD dev...

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Bibliographic Details
Published in:Immunity, Inflammation and Disease
Main Authors: Yu Qiu, Yueyang Zhao, Guiqiong He, Deqin Yang
Format: Article
Language:English
Published: Wiley 2025-02-01
Subjects:
blood‒brain barrier
neuroinflammation
NLRP3 inflammasome
outer membrane vesicles
Porphyromonas gingivalis
systemic inflammation
Online Access:https://doi.org/10.1002/iid3.70135

Internet

https://doi.org/10.1002/iid3.70135

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