Polyamine Metabolism Promotes the Progression of Thyroid Carcinoma by Regulating the Immune Phenotype of Tumor Associated Macrophages

ABSTRACT Polyamine metabolism is a key regulator of cellular proliferation and immune modulation, and its dysregulation is implicated in multiple carcinoma pathogenesis. Macrophages also greatly influence tumor progression by regulating the immune microenvironment. However, the role of polyamine met...

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Bibliographic Details

Published in:	Smart Medicine
Main Authors:	Haoran Ding, Lingling Xue, Shaoshi Zhu, Ziyu Wang, Huan Gui, Guang Zhang, Ning Tang, Haozhen Ren, Dayu Chen
Format:	Article
Language:	English
Published:	Wiley-VCH 2025-06-01
Subjects:	immunotherapy macrophage polyamine metabolism thyroid carcinoma
Online Access:	https://doi.org/10.1002/smmd.70009