TREM2 signaling pathway in sepsis-induced acute lung injury: physiology, pathology, and therapeutic applications

Sepsis emerges as a formidable and life-threatening condition, born from an unregulated immune response to infection, presenting a significant challenge to global health. A notable complication of sepsis is acute lung injury (ALI), marked by profound hypoxia, rampant inflammation, and the accumulati...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Hong-Lei Shen, Jing He, Fei Lin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	TREM2 sepsis ALI immunomodulation therapeutic application
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1546292/full