Congenital B-lymphoblastic leukemia with a cryptic MLL rearrangement and post-treatment evolution to mixed phenotype acute leukemia

Congenital leukemia is a rare event with a poor prognosis. We report a case of congenital leukemia with a cryptic rearrangement of MLL demonstrable only with RT-PCR. Interestingly, with treatment, the patient showed lineage plasticity of the leukemia with the development of monocytic lineage blasts...

Full description

Bibliographic Details

Published in:	Leukemia Research Reports
Main Authors:	Elizabeth Moschiano, Gordana Raca, Cecilia Fu, Paul K. Pattengale, Mathew J. Oberley
Format:	Article
Language:	English
Published:	Elsevier 2016-01-01
Subjects:	Congenital leukemia MLL rearrangement Lineage switch MPAL
Online Access:	http://www.sciencedirect.com/science/article/pii/S221304891630005X