Enteric bacteria induce IFNγ and Granzyme B from human colonic Group 1 Innate Lymphoid Cells

Group 1 Innate Lymphoid Cells (which include Natural Killer cells and ILC1s) aid in gut anti-bacterial defense through the production of IFNγ, which is critical for mobilizing protective responses against enteric pathogens. When intestinal epithelial barrier integrity is compromised, commensal bacte...

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Bibliographic Details

Published in:	Gut Microbes
Main Authors:	Moriah J. Castleman, Stephanie M. Dillon, Christine Purba, Andrew C. Cogswell, Martin McCarter, Edward Barker, Cara Wilson
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-11-01
Subjects:	group 1 ilcs ilc1 nk cells commensal bacteria il-12p70 il-18 il-1β colonic mucosa human ifnγ
Online Access:	http://dx.doi.org/10.1080/19490976.2019.1667723