Design, Synthesis and Herbicidal Activity of 1,2,4-Oxadiazole Compounds as Novel Light-Dependent Protochlorophyllide Oxidoreductase Inhibitors

Light-dependent protochlorophyllide oxidoreductase (LPOR, E.C.1.3.1.33) plays a crucial role in the biosynthesis of chlorophyll in plants. Therefore, inactivating LPOR can hinder the production of chlorophyll to achieve the effect of weed control. In this research, utilizing an active substructure s...

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Bibliographic Details
Published in:Molecules
Main Authors: Xiao Hu, Jing Miao, Yiyi Tian, Wennan Luo, Jixian Shang, Ruiyuan Liu, Huizhe Lu
Format: Article
Language:English
Published: MDPI AG 2025-10-01
Subjects:
LPOR inhibitor
1,2,4-oxadiazole compounds
herbicidal activity
molecular docking
crop safety
molecular dynamic simulation
Online Access:https://www.mdpi.com/1420-3049/30/19/3970

Internet

https://www.mdpi.com/1420-3049/30/19/3970

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