Assessment of fibrosis and vascularization of bone marrow stroma of chronic myeloid Leukemia patients treated with imatinib mesylate and their relationship with the cytogenetic response

Chronic Myeloid Leukemia (CML) is a myeloproliferative disease characterized by the presence of the Philadelphia chromosome (translocation between chromosomes 9 and 22), resulting in the formation of the hybrid BCR-ABL protein. Currently, the treatment of CML patients is performed with imatinib mesy...

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Bibliographic Details

Published in:	Brazilian Journal of Pharmaceutical Sciences
Main Authors:	Caroline Regina de Jesus, Lee I-Ching, Teresinha de Jesus Carvalho Neiva, Cidônia de Lourdes Vituri
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2011-06-01
Subjects:	Leucemia mielóide crônica Mesilato de imatinibe Medula óssea Fibrose Vascularização Chronic myeloid leukemia Imatinib mesylate Bone marrow Fibrosis Vascularization
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200012