Clinical prospects of WRN inhibition as a treatment for MSI tumours
Abstract The discovery of synthetic lethal interactions with genetic deficiencies in cancers has highlighted several candidate targets for drug development, with variable clinical success. Recent work has unveiled a promising synthetic lethal interaction between inactivation/inhibition of the WRN DN...
| Published in: | npj Precision Oncology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Online Access: | https://doi.org/10.1038/s41698-022-00319-y |