Development of an HPLC-MS/MS Method for the Determination of Silybin in Human Plasma, Urine and Breast Tissue

Silybin is a flavonolignan extracted from <i>Silybum marianum</i> with chemopreventive activity against various cancers, including breast. This study was designed to develop an HPLC-MS/MS method for the determination of silybin in human plasma, urine and breast tissue in early breast can...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Matteo Lazzeroni, Giovanna Petrangolini, José Antonio Legarreta Iriberri, Jaume Pascual Avellana, Digna Tost Robusté, Sara Cagnacci, Debora Macis, Valentina Aristarco, Bernardo Bonanni, Paolo Morazzoni, Harriet Johansson, Antonella Riva
Format:	Article
Language:	English
Published:	MDPI AG 2020-06-01
Subjects:	silybin silibinin Siliphos<sup>®</sup> breast cancer HPLC-MS/MS method
Online Access:	https://www.mdpi.com/1420-3049/25/12/2918