A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response

The mitochondrial unfolded protein response (UPRmt) has emerged as a predominant mechanism that preserves mitochondrial function. Consequently, multiple pathways likely exist to modulate UPRmt. We discovered that the tRNA processing enzyme, homolog of ELAC2 (HOE-1), is key to UPRmt regulation in Cae...

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書誌詳細

出版年:	eLife
主要な著者:	James P Held, Gaomin Feng, Benjamin R Saunders, Claudia V Pereira, Kristopher Burkewitz, Maulik R Patel
フォーマット:	論文
言語:	英語
出版事項:	eLife Sciences Publications Ltd 2022-04-01
主題:	mitochondria mitochondrial unfolded protein response ELAC2/HOE-1 tRNAs
オンライン･アクセス:	https://elifesciences.org/articles/71634