Genetically predicted small dense low-density lipoprotein cholesterol and ischemic stroke subtype: multivariable Mendelian randomization study

PurposeSmall dense low-density lipoprotein cholesterol (S-LDL-C) has been suggested as a particularly atherogenic factor for ischemic stroke (IS) in observational studies, but the causality regarding the etiological subtype remains unclear. This study aims to explore the causal effects of small dens...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Xiao Yu, Guangxun Shen, Yan Zhang, Cancan Cui, Yining Zha, Pingan Li, Lihong Li, Xu Wang, Guangxian Nan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	low-density lipoprotein cholesterol (LDL-C) subfractions small low-density lipoprotein cholesterol (S-LDL-C) ischemic stroke (IS) large artery stroke (LAS) Mendelian randomization low-density lipoprotein cholesterol (LDL-C)
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1404234/full