Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1

Abstract Cardiolipin is a mitochondria-specific phospholipid that forms heterotypic interactions with membrane-shaping proteins and regulates the dynamic remodeling and function of mitochondria. However, the precise mechanisms through which cardiolipin influences mitochondrial morphology are not wel...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Sirikrishna Thatavarthy, Luciano A. Abriata, Fernando Teixeira Pinto Meireles, Kelly E. Zuccaro, Akhil Gargey Iragavarapu, Gabriela May Sullivan, Frank R. Moss, Adam Frost, Matteo Dal Peraro, Halil Aydin
Format: Article
Language:English
Published: Nature Portfolio 2025-09-01
Online Access:https://doi.org/10.1038/s41467-025-63813-4