Blood‐brain barrier dysfunction and decreased transcription of tight junction proteins in epileptic dogs

Abstract Background Epilepsy in dogs and humans is associated with blood‐brain barrier (BBB) dysfunction (BBBD), which may involve dysfunction of tight junction (TJ) proteins, matrix metalloproteases, and astrocytes. Imaging techniques to assess BBB integrity, to identify potential treatment strateg...

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Bibliographic Details

Published in:	Journal of Veterinary Internal Medicine
Main Authors:	Erez Hanael, Shelly Baruch, Rotem Kalev Altman, Orit Chai, Kira Rapoport, Dana Peery, Alon Friedman, Merav H. Shamir
Format:	Article
Language:	English
Published:	Wiley 2024-07-01
Subjects:	blood‐brain barrier claudin 5 CNS disorders epilepsy Kir 4.1 MMP9
Online Access:	https://doi.org/10.1111/jvim.17099