The effect of 1,25(OH)2D3 on Dickkopf-1 methylation in colorectal cancer

Abstract Background Vitamin D is a fat-soluble vitamin that has a protective role in colorectal cancer. Several studies have identified the association between vitamin D and changes in DNA methylation in different types of tumours. Dickkopf-1 (DKK1) inhibits the Wnt/β-catenin signalling pathway, and...

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Bibliographic Details
Published in:Clinical Epigenetics
Main Authors: Hongyan Sun, Liehao Yang, Nan Li, Yue Hu, Qianying Hu, Zilong Zhou, Xianling Cong
Format: Article
Language:English
Published: BMC 2025-03-01
Subjects:
1,25(OH)2D3
DNA methylation
DKK1
Colorectal cancer
Online Access:https://doi.org/10.1186/s13148-025-01857-5

Internet

https://doi.org/10.1186/s13148-025-01857-5

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