Inhibiting the DNA damage repair of HNSCC cells in combination with normo-fractionated radiotherapy influences clonogenicity, senescence and expression of NK cell activation markers
Abstract Treatment of head and neck squamous cell carcinomas (HNSCC) remains challenging with regards to radioresistance, particularly of Human Papilloma Virus (HPV)-negative tumors. Several new approaches are currently under pre-clinical and clinical investigation. Combination of radiotherapy (RT)...
| Published in: | Scientific Reports |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Online Access: | https://doi.org/10.1038/s41598-025-17858-6 |