Novel Activity Detection Algorithm to Characterize Spontaneous Stepping During Multimodal Spinal Neuromodulation After Mid-Thoracic Spinal Cord Injury in Rats

A mid-thoracic spinal cord injury (SCI) severely impairs activation of the lower limb sensorimotor spinal networks, leading to paralysis. Various neuromodulatory techniques including electrical and pharmacological activation of the spinal networks have been successful in restoring locomotor function...

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Bibliographic Details

Published in:	Frontiers in Systems Neuroscience
Main Authors:	Raymond Chia, Hui Zhong, Bryce Vissel, V. Reggie Edgerton, Parag Gad
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-01-01
Subjects:	sub-threshold spinal cord stimulation spinal cord injury spontaneous cage activity EMG muscle coordination strychnine
Online Access:	https://www.frontiersin.org/article/10.3389/fnsys.2019.00082/full