Effects of super-enhancers in cancer metastasis: mechanisms and therapeutic targets

Abstract Metastasis remains the principal cause of cancer-related lethality despite advancements in cancer treatment. Dysfunctional epigenetic alterations are crucial in the metastatic cascade. Among these, super-enhancers (SEs), emerging as new epigenetic regulators, consist of large clusters of re...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Shenglan Liu, Wei Dai, Bei Jin, Feng Jiang, Hao Huang, Wen Hou, Jinxia Lan, Yanli Jin, Weijie Peng, Jingxuan Pan
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	Super-enhancers Metastasis Molecular mechanisms Therapeutic targets
Online Access:	https://doi.org/10.1186/s12943-024-02033-8