Fer governs mTORC1 regulating pathways and sustains viability of pancreatic ductal adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with a high percentage of morbidity. The deciphering and identification of novel targets and tools for intervening with its adverse progression are therefore of immense importance. To address this goal we adopted a specific inhi...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Ilan Schrier, Orel Slotki-Itzchakov, Yoav Elkis, Nofar Most-Menachem, Orit Adato, Debora Fitoussi-Allouche, Sally Shpungin, Ron Unger, Uri Nir
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	Fer E260 pancreatic ductal adenocarcinoma mitochondria AMPK mTORC1
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1427029/full