Clonal structure and the specificity of vaccine-induced T cell response to SARS-CoV-2 Spike protein

Adenovirus vaccines, particularly the COVID-19 Ad5-nCoV adenovirus vaccine, have emerged as promising tools in the fight against infectious diseases. In this study, we investigated the structure of the T cell response to the Spike protein of the SARS-CoV-2 virus used in the COVID-19 Ad5-nCoV adenovi...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Saveliy A. Sheetikov, Alexandra A. Khmelevskaya, Ksenia V. Zornikova, Ivan V. Zvyagin, Alina S. Shomuradova, Yana V. Serdyuk, Naina T. Shakirova, Iuliia O. Peshkova, Aleksei Titov, Dmitrii S. Romaniuk, Irina A. Shagina, Dmitry M. Chudakov, Dmitry O. Kiryukhin, Olga V. Shcherbakova, Ekaterina G. Khamaganova, Vitalina Dzutseva, Andrei Afanasiev, Apollinariya V. Bogolyubova, Grigory A. Efimov
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Subjects:	T cell vaccination SARS-CoV-2 adenoviral vaccine T cell receptor spike protein
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1369436/full