Candidate Therapeutics by Screening for Multitargeting Ligands: Combining the CB2 Receptor With CB1, PPARγ and 5-HT4 Receptors

In recent years, the cannabinoid type 2 receptor (CB2R) has become a major target for treating many disease conditions. The old therapeutic paradigm of “one disease-one target-one drug” is being transformed to “complex disease-many targets-one drug.” Multitargeting, therefore, attracts much attentio...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shayma El-Atawneh, Amiram Goldblum
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-02-01
Subjects:	cannabinoid receptors 2 (CB2R) multitargeting ISE virtual screening inflammation neuroprotective
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.812745/full