A Role for Frizzled and Their Post-Translational Modifications in the Mammalian Central Nervous System

The Wnt pathway is a key signalling cascade that regulates the formation and function of neuronal circuits. The main receptors for Wnts are Frizzled (Fzd) that mediate diverse functions such as neurogenesis, axon guidance, dendritogenesis, synapse formation, and synaptic plasticity. These processes...

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發表在:	Frontiers in Cell and Developmental Biology
Main Authors:	Patricia Pascual-Vargas, Patricia C. Salinas
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2021-08-01
主題:	post-translational modification Frizzled receptors Wnt signalling CNS connectivity trafficking
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fcell.2021.692888/full