Dissecting the Crosstalk Between Nrf2 and NF-κB Response Pathways in Drug-Induced Toxicity

Nrf2 and NF-κB are important regulators of the response to oxidative stress and inflammation in the body. Previous pharmacological and genetic studies have confirmed crosstalk between the two. The deficiency of Nrf2 elevates the expression of NF-κB, leading to increased production of inflammatory fa...

詳細記述

書誌詳細

出版年:	Frontiers in Cell and Developmental Biology
主要な著者:	Wen Gao, Lin Guo, Yan Yang, Yu Wang, Shuang Xia, Hui Gong, Bi-Kui Zhang, Miao Yan
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2022-02-01
主題:	Nrf2 NF-κB crosstalk drug-induced toxicity toxic reactions
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fcell.2021.809952/full