THE ATAXIA-TELANGIECTASIA MUTATED (ATM) GENE PLAYS A PIVOTAL ROLE IN THE REPAIR OF DNA IN CASES OF MYELODYSPLASTIC NEOPLASM

Myelodysplastic Neoplasm (MDS) is an age-associated neoplasia characterized by frequent epigenetic abnormalities being hypermethylation the most common, frequently associated with transformation to acute myeloid leukemia (AML). DNA repair genes have been constantly downregulated in MDS during progre...

Full description

Bibliographic Details

Published in:	Hematology, Transfusion and Cell Therapy
Main Authors:	JVC Goes, LR Sampaio, RTG Oliveira, DP Borges, RDB Dias, CLA Araujo, PRC Passos, HLR Junior, SMM Magalhães, RF Pinheiro
Format:	Article
Language:	English
Published:	Elsevier 2024-10-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2531137924010885