Pacritinib abrogates the lupus phenotype in ABIN1[D485N] mice

Objective The aim of the study was to investigate whether the IRAK1/JAK2/Flt3 inhibitor pacritinib prevents disease development in the lupus-prone ABIN1[D485N] knock-in mouse.Methods ABIN1[D485N] knock-in mice aged 8 weeks were fed for 10 weeks on a diet containing pacritinib. Body weight was monito...

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Bibliographic Details
Published in:Lupus Science and Medicine
Main Authors: Philip Cohen, Tsvetana Petrova, Sambit K Nanda, Cheryl Scudamore, Clara Figueras-Vadillo
Format: Article
Language:English
Published: BMJ Publishing Group 2023-01-01
Online Access:https://lupus.bmj.com/content/10/1/e000822.full