Yolk sac tumor and dysgerminoma in the left gonad following gonadoblastoma in the right gonad in a 46,XY DSD with a novel SRY missense mutation: a case report

Abstract Background Approximately 10–15% of 46,XY disorders of sex development (DSDs) have an SRY mutation residing in the high mobility group (HMG) domain. Here, we present a case of 46,XY DSD caused by a novel missense mutation in the HMG region of SRY rapidly progressing to germ cell tumors (GCTs...

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Bibliographic Details

Published in:	BMC Pregnancy and Childbirth
Main Authors:	Chengxiu Xie, Jian Cai, Nan Li, Ping Hua, Zexuan Yang, Xia Yu, Dongmei Tang, Yu Hu, Qingsong Liu
Format:	Article
Language:	English
Published:	BMC 2023-01-01
Subjects:	Disorders of sex development (DSD) Yolk sac tumor Dysgerminoma Gonadoblastoma (GB) Case report
Online Access:	https://doi.org/10.1186/s12884-022-05317-3