Novel insights in the pathomechanism of Brugada syndrome and fever‐related type 1 ECG changes in a preclinical study using human‐induced pluripotent stem cell‐derived cardiomyocytes

Abstract Background Brugada syndrome (BrS) is causing sudden cardiac death (SCD) mainly at young age. Studying the underlying mechanisms associated with BrS type I electrocardiogram (ECG) changes in the presence of fever and roles of autophagy for BrS remains lacking. Objectives We sought to study t...

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Bibliographic Details

Published in:	Clinical and Translational Medicine
Main Authors:	Yingrui Li, Hendrik Dinkel, Dalia Pakalniskyte, Alexandra Viktoria Busley, Lukas Cyganek, Rujia Zhong, Feng Zhang, Qiang Xu, Lasse Maywald, Assem Aweimer, Mengying Huang, Zhenxing Liao, Zenghui Meng, Chen Yan, Timo Prädel, Lena Rose, Alexander Moscu‐Gregor, Alyssa Hohn, Zhen Yang, Lin Qiao, Andreas Mügge, Xiaobo Zhou, Ibrahim Akin, Ibrahim El‐Battrawy
Format:	Article
Language:	English
Published:	Wiley 2023-03-01
Subjects:	autophaghy Brugada syndrome cardiac arrest induced pluripotent stem cells inflammation sudden cardiac death
Online Access:	https://doi.org/10.1002/ctm2.1130