3D imaging of Sox2 enhancer clusters in embryonic stem cells
Combinatorial cis-regulatory networks encoded in animal genomes represent the foundational gene expression mechanism for directing cell-fate commitment and maintenance of cell identity by transcription factors (TFs). However, the 3D spatial organization of cis-elements and how such sub-nuclear struc...
| Published in: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2014-12-01
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| Subjects: | |
| Online Access: | https://elifesciences.org/articles/04236 |