Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells

Objective: The transcription factors (TF) Foxa2 and Pdx1 are key regulators of beta-cell (β-cell) development and function. Mutations of these TFs or their respective cis-regulatory consensus binding sites have been linked to maturity diabetes of the young (MODY), pancreas agenesis, or diabetes susc...

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Bibliographic Details

Published in:	Molecular Metabolism
Main Authors:	Aimée Bastidas-Ponce, Sara S. Roscioni, Ingo Burtscher, Erik Bader, Michael Sterr, Mostafa Bakhti, Heiko Lickert
Format:	Article
Language:	English
Published:	Elsevier 2017-06-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877817300510