P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation

Inflammation is a common process associated with numerous vascular pathologies. We hypothesized that targeting the inflamed endothelium by coupling a peptide with high affinity for P-selectin to the surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding to ac...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Mediators of Inflammation
المؤلفون الرئيسيون: Viorel Simion, Cristina Ana Constantinescu, Daniela Stan, Mariana Deleanu, Monica Madalina Tucureanu, Elena Butoi, Ileana Manduteanu, Maya Simionescu, Manuela Calin
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2016-01-01
الوصول للمادة أونلاين:http://dx.doi.org/10.1155/2016/1625149