Altered Behavior in Mice Socially Isolated During Adolescence Corresponds With Immature Dendritic Spine Morphology and Impaired Plasticity in the Prefrontal Cortex

Mice socially isolated during adolescence exhibit behaviors of anxiety, depression and impaired social interaction. Although these behaviors are well documented, very little is known about the associated neurobiological changes that accompany these behaviors. It has been hypothesized that social iso...

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Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	William E. Medendorp, Eric D. Petersen, Akash Pal, Lina-Marie Wagner, Alexzander R. Myers, Ute Hochgeschwender, Kenneth A. Jenrow
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Subjects:	neuronal plasticity social isolation social interaction dendritic spines long term potentiation prefrontal cortex
Online Access:	http://journal.frontiersin.org/article/10.3389/fnbeh.2018.00087/full