A deoxynucleoside triphosphate triphosphohydrolase promotes cell cycle progression in Caulobacter crescentus

ABSTRACT Intracellular pools of deoxynucleoside triphosphates (dNTPs) are strictly maintained throughout the cell cycle to ensure accurate and efficient DNA replication. DNA synthesis requires an abundance of dNTPs, but elevated dNTP concentrations in nonreplicating cells delay entry into S phase. E...

Full description

Bibliographic Details

Published in:	Journal of Bacteriology
Main Authors:	Chandler N. Hellenbrand, David M. Stevenson, Katarzyna A. Gromek, Daniel Amador-Noguez, David M. Hershey
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-06-01
Subjects:	dNTPs DNA replication Caulobacter crescentus cell cycle control
Online Access:	https://journals.asm.org/doi/10.1128/jb.00145-25