Functional high-throughput screen identifies microRNAs that promote butyrate-induced death in colorectal cancer cells

The gut fermentation product butyrate displays anti-cancer properties in the human proximal colon, including the ability to inhibit proliferation and induce apoptosis in colorectal cancer (CRC) cells. A natural histone deacetylase inhibitor (HDACi), butyrate can alter histone acetylation patterns in...

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Bibliographic Details

Published in:	Molecular Therapy: Nucleic Acids
Main Authors:	Saira R. Ali, Karen J. Humphreys, Kaylene.J. Simpson, Ross A. McKinnon, Robyn Meech, Michael Z. Michael
Format:	Article
Language:	English
Published:	Elsevier 2022-12-01
Subjects:	MT: non-coding RNAs microRNAs colorectal cancer butyrate histone acetylation high-throughput screen
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253122002360