Re-Configuration of Sphingolipid Metabolism by Oncogenic Transformation

The sphingolipids are one of the major lipid families in eukaryotes, incorporating a diverse array of structural variants that exert a powerful influence over cell fate and physiology. Increased expression of sphingosine kinase 1 (SPHK1), which catalyses the synthesis of the pro-survival, pro-angiog...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Anthony S. Don, Xin Y. Lim, Timothy A. Couttas
Format:	Article
Language:	English
Published:	MDPI AG 2014-03-01
Subjects:	sphingolipid cancer metabolism sphingosine 1-phosphate sphingosine kinase ceramide glucosylceramide sphingomyelin sphingomyelinase glycolipid
Online Access:	http://www.mdpi.com/2218-273X/4/1/315