The First Human Vulvar Intraepithelial Neoplasia Cell Line with Naturally Infected Episomal HPV18 Genome

Persistent infection with high-risk HPV leads to cervical cancers and other anogenital cancers and head and neck carcinomas in both men and women. There is no effective drug fortreating HPV infection and HPV-associated carcinomas, largely due to a lack of models of natural HPV infection and the comp...

Full description

Bibliographic Details

Published in:	Viruses
Main Authors:	Ming Wu, Xiu Zhang, Yiyi Kang, Yaqi Zhu, Zhaoyu Su, Jun Liu, Wei Zhang, Hong Chen, Hui Li
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	conditional reprogramming (CR) vulvar intraepithelial neoplasia (VIN) cells episomal HPV18 air-liquid interface (ALI) culture life cycle
Online Access:	https://www.mdpi.com/1999-4915/14/9/2054